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Signs of stomach bleedingbloody or tarry stoolscoughing up blood or vomit that looks like coffee grounds.

High blood sugarincreased thirstincreased urinationhungerfruity breath odornausealoss of appetitedrowsinessblurred visionconfusion;

Tacrolimus may cause diabetesTell your doctor or pharmacist if you experience any of the following symptoms of high blood sugarincreased thirst/hungerfrequent urination.

The use of Prograf in liver transplant recipients experiencing post-transplant hepatic impairment may be associated with increased risk of developing renal insufficiency related to high whole-blood concentrations of tacrolimusThese patients should be monitored closely and dosage adjustments should be consideredSome evidence suggests that lower doses should be used in these patientssee Dosage In Adult KidneyLiverOr Heart Transplant PatientsUse in Specific Populations and CLINICAL PHARMACOLOGY

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cimetidine tagamet ; conivaptan vaprisol ; imatinib gleevec ; isoniazid for treating tuberculosis ; tacrolimus prograf ; an antibiotic such as clarithromycin biaxin , dalfopristin quinupristin synercid , erythromycin e.

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